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Berberine - the natural alternative to Ozempic

Today Berberine is being touted by all the Western health coaches as a miracle herb which acts like Nature’s Ozempic.

But did you know that Indian Ayurvedic Rishis prescribed Berberine (Berberis aristata) aka Dāruharidrā for prameha (urinary disorders, such as diabetes) & controlling insulin several thousands of years ago?

Here are some ancient references :

  • Caraka Saṃhitā (Cikitsāsthāna 6.45–46, Prameha Cikitsā) Caraka prescribes Nityapāna (daily decoction) of bitter herbs for Prameha. “Nyagrodhādi gaṇo vā’tha prameheṣu pradīyate || Dāruharidrā triphalā mustā lodhrā caiva prayojayet |” (Cikitsāsthāna 6.45–46) Translation: For Prameha, the Nyagrodhādi group of herbs is prescribed. One should also use Dāruharidrā, Triphalā, Mustā, and Lodhrā. This is one of the earliest direct mentions of Dāruharidrā for diabetes-like conditions.

  • Suśruta Saṃhitā (Cikitsāsthāna 12.10, Prameha Cikitsā) “Dāruharidrātriphalaśṛṅgāṭaka-lodhrāni prameheṣu prayojayet” Translation: In Prameha, Dāruharidrā, Triphalā, Śṛṅgāṭaka, and Lodhrā are prescribed.

  • Aṣṭāṅga Hṛdaya (Cikitsāsthāna 10.17–18, Prameha Cikitsā) “Dāruharidrā triphalā mustā lodhrā ca pramehajit ||” Translation: Dāruharidrā, Triphalā, Mustā, and Lodhrā are destroyers of Prameha.

  • Bhāvaprakāśa Nighaṇṭu (Harītakyādi Varga, 197–201) In the commentary on Prameha, it specifically highlights: “Dāruharidrā pramehaghnaḥ” Translation: Dāruharidrā alleviates Prameha (urinary disorders including diabetes).

So across all three classical Ayurvedic texts (Caraka, Suśruta, Aṣṭāṅga Hṛdaya), Dāruharidrā is repeatedly grouped with Triphalā, Mustā, Lodhrā as a key anti-diabetic drug. Modern pharmacology confirms this with berberine’s hypoglycemic activity.

Now how did they know such specific details about Daruharidra thousands of years ago is the real mind boggling question.

Berberine

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